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Management of the pregnant patient with pulmonary disease must take into account the anatomic and physiological changes affecting the respiratory system in pregnancy although management is similar to that in the non pregnant patient the welfare of the fetus must be considered in radiological investigations and pharmacological therapy. Respiratory physiology of pregnancy physiology masterclass pregnancy during disease in addition to the biochemical and mechanical factors many illnesses produce significant negative effects on respiratory maternal and fetal outcomes the sensitivity of the respiratory center in pregnancy and after administration of progesterone . Review article respiratory diseases in pregnancy srikanti raghu surya kiran pulivarthi department of tb and chest diseases guntur medical college government fever hospital guntur abstract pulmonary diseases are one of the major indirect causes of maternal deaths pregnancy is a unique physiologi cal. Mechanical ventilation in pregnancy stephen e lapinsky mount sinai hospital toronto respiratory disease predelivery pao 2 fio2 delivery neonatal weight g oi decrease compliance increase lapinsky et al 2014 delivery of the fetus. Disease may also cause respiratory disease through the developmentofchoriocarcinoma whichcommonlypro duces multiple discrete pulmonary metastases and oc casionallypleuraleusions other pulmonary disorders in pregnancy asthma asthma aects 510 of the population and can there forebe expected to involve a similar proportion of wo